Domain analysis of the Edwardsiella tarda ferric uptake regulator
نویسندگان
چکیده
منابع مشابه
Domain analysis of the Edwardsiella tarda ferric uptake regulator.
Recent studies have shown that the ferric uptake regulator (Fur) of Edwardsiella tarda (Fur(Et)) shares high sequence identity with the Escherichia coli Fur (Fur(Ec)) at the N-terminal DNA-binding region. In the present study, the functional importance of the C-terminal region of Fur(Et) was investigated. It was found that Fur(Et) bearing deletion of the C-terminal 12 residues still possesses m...
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Inorganic phosphate (P(i)) and iron are essential nutrients that are depleted by vertebrates as a protective mechanism against bacterial infection. This depletion, however, is sensed by some pathogens as a signal to turn on the expression of virulence genes. Here, we show that the PhoB-PhoR two-component system senses changes in P(i) concentration, whereas the ferric uptake regulator (Fur) sens...
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ژورنال
عنوان ژورنال: The Journal of General and Applied Microbiology
سال: 2009
ISSN: 1349-8037,0022-1260
DOI: 10.2323/jgam.55.351